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Glossary of Terms

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Lead
Symbol: Pb
Atomic Number: 82

Somewhere between 400,000 and 600,000 tons of lead per year go into our atmosphere, onto our earth, into our food, and into our body and tissues. Unlike most chemicals for which the health impacts of low-level exposure are still uncertain, exposure to lead, even at very low levels, is very toxic.

Lead is the most common toxic mineral as well as being the most abundant contaminant of our environment and our body. Fortunately, lead is not the most toxic element; cadmium and mercury are worse. Lead has a slightly sweet taste and children often eat or suck on the paint chips from houses leading to many cases of lead poisoning.

The most widespread source of environmental contamination is from the addition of tetraethyl lead to gasoline as an anti-knock, higher-octane additive. Research has shown that lead is a neurotoxin and commonly generates abnormal brain and nerve function. It enters the brain and can, in pregnant or lactating mothers, contaminate the in utero fetus and breast milk.

Lead is commonly stored in the bones as shown by "lead lines" in the bones on X-rays. It is also stored in the adrenals, thyroid, aorta, liver and other soft tissues.

In just the United States, it has been estimated that approximately 1.3 million tons of lead is used yearly in solder, batteries, pottery, pigments, gasoline, paint, and many other useful substances. Other sources of lead contamination are lead industries, mining, and smelting, piping, fixtures, insecticides and solder. Due to its unique properties, it has been used widely as a pigment and drying agent in primers, paints and enamels, inks, oils, resins, and other surface coatings for centuries. In drinking water, the major source of lead is from the corrosion of leaded plumbing materials in the water supply and household distribution systems.

Lead most likely interferes with functions performed by essential minerals such as calcium, copper and zinc. In the human system, lead interrupts several red blood cell enzyme systems, including delta-aminolevulinic dehydratase and ferrochelatase. It may also reduce hemoglobin synthesis and can react with cell membranes. This may cause increased permeability of the cells and cause damage to or even death of those cells. In the brain, lead may create abnormal function by inactivating important zinc-, copper-, and iron-dependent enzymes.

The term lead comes from the Latin word plumbum (lead).


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